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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Int J Obes (Lond). 2014 Jan 16;38(9):1228–1233. doi: 10.1038/ijo.2014.6

Figure 4. GR mediated cortisol-regulation of adipokine production in differentiated human adipocytes.

Figure 4

GR or MR silenced human adipocytes were starved for GCs overnight and treated with 200 nM cortisol for 24h. (A) Leptin mRNA. (B) Leptin secretion. (C) Adiponectin mRNA. (D) Adiponection secretion. (E) IL-6 mRNA. (F) IL-6 secretion. Interaction GR or MR siRNA and cortisol by 2 way-ANOVA, p<0.05, p<0.01, p<0.001 for the n=4-5. Effects of cortisol treatment vs. control: *, p<0.05, **, p<0.01 by paired T test.