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. Author manuscript; available in PMC: 2015 Feb 9.
Published in final edited form as: Nephron Exp Nephrol. 2008 Sep 8;110(2):e49–e58. doi: 10.1159/000153245

Table 3.

Basic parameters in experimental groups

Parameters VH1 (n = 5) CsA1 (n = 5) VH4 (n = 5) CsA4 (n = 5)
Body weight, g 215±6 225±4 300±4 245±5*
Water intake, ml/24 h 14±2 17±3 15±1 34±6*
Blood pressure, mm Hg 125±4 128±5 122±3 124±3
Urine osmolality, mosm/kg 1,212±430 1,112±230 1,139±264 560±28*
FENa, % 0.03±0.01 0.02±0.01 0.03±0.01 0.04±0.01
TcW, ml/24 h 48±4 41±7 43±3 25±3*
BUN, mg/dl 8.0±0.6 18.5±22.1* 10.0±0.9 33.0±2.0*
SCr, mg/dl 0.56±0.02 0.62±0.02 0.58±0.02 1.90±0.08*
TIF, % 0.0±0.0 3.2±1.4 0.0±0.0 28.5±3.0*

Values are means ± SEM. n = Number of rats. VH = Vehicle-treated group; CsA = cyclosporine A; FENa = fractional excretion of sodium; TcW = free-water reabsorption; BUN = blood urea nitrogen; SCr = serum creatinine; TIF = tubulointerstitial fibrosis.

*

p < 0.05 vs. VH.