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. Author manuscript; available in PMC: 2015 Feb 9.
Published in final edited form as: Prog Brain Res. 1999;120:119–132. doi: 10.1016/s0079-6123(08)63550-5

Fig.4.

Fig.4

Effects of MRS 2219 (A) and MRS 2220 (B) on inward current induced by ATP, at the indicated concentrations, of recombinant rat P2X1 (3 μM), P2X2 (10 μM), P2X3 (1 μM), and P2X4 (30 μM) receptors, expressed in Xenopus oocytes, using the twin electrode voltage clamping technique. The agonist concentrations correspond approximately to the EC70 values. IC50 values for MRS 2220 (n = 4) at P2X1 and P2X3 receptors were 10.2 ± 2.6 μM and 58.3 ± 0.1 μM, respectively.