Fig. 2.

Example of NAWM (green) and WMH (magenta) masks overlaid onto the MRI parametric maps for a typical subject, and the corresponding box plots for the average values of each parameter measured in both tissue types across the cohort: (A) and (E) for FA, (B) and (F) for MD, (C) and (G) for MTR and (D) and (H) for T1 relaxation time. Abbreviations: FA, fractional anisotropy; MD, mean diffusivity; MRI, magnetic resonance imaging; MTR, magnetization transfer ratio; NAWM, normal-appearing white matter; WMH, white matter hyperintensity. (For interpretation of the references to color in this Figure, the reader is referred to the web version of this article.)