Fig. 3.

A, B Luciferase activity of reporter constructs. A Promoter activities were determined in transfected mouse aortic smooth muscle cells. Activity is expressed in percentages relative to the ratios of luciferase/β-galactosidase activities with the “CT11” promoter as 100%. Bars Means ± SE from four experiments (n=12 individual wells). P<0.001 by ANOVA. B 3’UTR function was examined by transfection of constructs in 293 cells (four experiments) and in mouse aortic smooth muscle cells (four experiments). Activities are expressed as percentages relative to that of “4-plus” variant as 100%. Bars Means ± SE from the eight experiments combined (n=18 individual wells). P<0.0001 by ANOVA. Asterisks in A, B indicate the constructs whose expression differs significantly from others