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. Author manuscript; available in PMC: 2015 Feb 10.
Published in final edited form as: J Surg Oncol. 2013 Dec 17;109(6):533–541. doi: 10.1002/jso.23531

TABLE III.

Univariate and Multivariate Analysis of Risk Factors Associated With Overall Survival for Patients With HCC Within Milan Criteria (n = 176)

Univariate
Multivariate
Variable HR (95% CI) P-Value HR (95% CI) P-Value
Age 1.02 (0.98–2.05) 0.36  
Gender, male 1.40 (0.70–2.80) 0.34  
Race
 White Ref Ref
 Black 1.97 (1.05–3.69) 0.03   1.57 (0.82–3.00) 0.18
 Other 0.71 (0.28–1.82) 0.47   0.56 (0.21–1.47) 0.24
ASA class
 2 Ref
 3 0.55 (0.12–2.39) 0.42  
 4 0.30 (0.07–1.24) 0.11  
Hepatitis B 1.68 (0.96–2.92) 0.07  
Hepatitis C 1.54 (0.85–2.77) 0.15  
Alcohol abuse 1.64 (0.90–2.99) 0.11  
Tumor size 1.16 (0.96–1.41) 0.15  
Macrovascular invasion 3.40 (1.35–8.61) 0.01   3.56 (1.32–9.58) 0.01
Microvascular invasion 1.51 (0.80–2.83) 0.20  
Tumor grade, poor 2.30 (1.12–4.72) 0.02   1.68 (0.78–3.62) 0.19
Resection 2.20 (1.26–3.85) 0.006 2.23 (1.20–4.14) 0.01

HCC, hepatocellular carcinoma; ASA, American Society of Anesthesiology; HR, hazard ratio; CI, confidence interval.

The bolded text appearing in Table designates statistical significance (P ≤ 0.05).