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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Pediatr Res. 2014 Jun 18;76(3):238–244. doi: 10.1038/pr.2014.82

Table 2.

Echocardiography characteristics before and after treatment of the groups

Short course of oral paracetamol
Long course of oral paracetamol
Intravenous paracetamol
Pre Post P Pre Post P Pre Post P
PDA diameter (mm) 2.8 (2.6–3.0) 3.1 (3.0–3.1) 0.04 2.4 (2.2–2.5) 1.4 (1.0–1.8) 0.03 3.7 (3.2–4.3) 0 (0–1.1) <0.01
Left atrium:aortic ratio 2.4 (2.3–2.5) 2.5 (2.2–2.7) 0.46 2.0 (1.8–2.3) 1.8 (1.8–1.9) 0.07 2.00 (1.85–2.80) 1.85 (1.31–2.24) 0.03
IVRT (msec) 36 (34–37) 36 (34–37) 0.29 39 (35–41) 52 (47–57) 0.08 44 (37–57) 48 (43–54) 0.67
LVO (ml/min/kg) 328 (305–385) 358 (334–555) 0.27 435 (395–533) 321 (246–350) 0.03 271 (238–390) 192 (184–224) 0.03
LVEDD (mm) 16 (12–20) 18 (16–21) 0.19 16 (13–17) 16 (11–17) 0.68 14 (12–16) 13 (11–13) 0.09

Data are presented as medians (interquartile range).

IVRT, isovolumic relaxation time; LVO, left ventricular output; LVEDD, left ventricular end diastolic velocity; PDA, patent ductus arteriosus.