Table 3.
Cox Proportional Hazards Model Treating Missing HmR Status As a Separate Category and Using Multiple Imputation for Other Missing Covariates While Treating Age As Categoric
| Variable | OS |
RFS |
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| HDC v control | 0.94 | 0.87 to 1.02 | .13 | 0.87 | 0.81 to 0.93 | < .001 |
| Age ≥ 50 years v < 50 years | 0.97 | 0.89 to 1.06 | .55 | 0.91 | 0.84 to 0.98 | .019 |
| HmR status positive v negative | 0.59 | 0.54 to 0.64 | < .001 | 0.68 | 0.63 to 0.73 | < .001 |
| Square root of positive lymph nodes | 1.28 | 1.22 to 1.34 | < .001 | 1.26 | 1.20 to 1.31 | < .001 |
Abbreviations: HDC, high-dose chemotherapy; HmR, hormone receptor; HR, hazard ratio; OS, overall survival; RFS, relapse-free survival.