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Gross morphology of colon adenoma tumors (black arrows) in colons from AOM-treated 15-PGDH WT (A, C, E and G) and 15-PGDH KO mice (B, D, F and H) administered control (A and B), aspirin (C and D), celecoxib (E and F) or sulindac (G and H) containing diets. (I and J) Hematoxylin and eosin staining of a representative colon adenoma at ×4 magnification (I) and ×10 magnification (J).
