Table 1.
Parasitological cure rate of praziquantel treatment in relation to demographic factors, HIV-1, CD4 + count levels and S. mansoni infection intensities
| Variable | No. of individuals infected at baseline | No. of individuals cured after treatment (%) | χ 2 | P-value* |
|---|---|---|---|---|
| Overall | 555 | 343 (61.80) | ||
| Sex | ||||
| Female | 241 | 148 (62.10) | 0.028 | 0.87 |
| Male | 314 | 195 (62.10) | ||
| Age group | ||||
| 21–30 | 241 | 149 (61.83) | 3.5550 | 0.31 |
| 31–40 | 177 | 103 (58.19) | ||
| 41–50 | 84 | 59 (70.24) | ||
| 51–60 | 53 | 32 (60.38) | ||
| Occupation | ||||
| Small-scale business | 66 | 38 (57.58) | 0.5780 | 0.75 |
| Farming | 376 | 235 (62.50) | ||
| Fishing | 113 | 70 (61.95) | ||
| Village of residence | ||||
| Igombe | 112 | 67 (59.82) | 3.0418 | 0.39 |
| Igalagala | 98 | 54 (55.10) | ||
| Kayenze | 219 | 140 (63.93) | ||
| Sangabuye | 126 | 82 (65.08) | ||
| Time of residence (years) | ||||
| 3–5 | 97 | 65 (67.01) | 1.8745 | 0.59 |
| 6–10 | 83 | 53 (63.86) | ||
| 11–20 | 136 | 83 (61.03) | ||
| ≥21 | 239 | 142 (59.41) | ||
| HIV-1 serostatus | ||||
| Negative | 526 | 329 (62.55) | 2.3714 | 0.12 |
| Positive | 29 | 14 (48.28) | ||
| CD4 + count levels (cells/μL) | ||||
| <350 | 17 | 7 (43.75) | 1.4479 | 0.23 |
| >350 | 12 | 8 (66.67) | ||
| S. mansoni infection intensities | ||||
| Light (1–100 epg) | 234 | 143 (61.11) | 0.9542 | 0.62 |
| Moderate (101–399 epg) | 162 | 105 (64.81) | ||
| Heavy (≥400 epg) | 159 | 95 (59.75) | ||
*P-value by chi-square (χ2).