Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Feb 10;9:8. doi: 10.3389/fnint.2015.00008

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Rossi, Go, Murphy, Fu, Morizio and Yin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

In vivo wireless stimulation of striatonigral neurons drives behavior. (A) Photograph of a mouse with wireless headstage. (B) Schematic illustration of LED placement within the dorsal striatum of D1-ChR2 mice. (C) Representative serial coronal sections through the shank track. LED placement is indicated by arrowhead. Scale bars are 1 mm. (D) High power (32 mW) LED stimulation of striatonigral neurons induces twitching in freely behaving mice in a frequency dependent manner. (E) Behavioral response to LED stimulation is stable 41 days after the initial tests. (F) Control mice that lack opsin expression show no response to stimulation. The dotted lines are linear regression lines. (G) Proportion of time D1-ChR2 mice spent turning during low power (16 mW) stimulation. Values are mean ± s.e.m.