Figure 5.
Expression levels of caspase-12, JNK, and CHOP in C17.2 cells. After the C17.2 cells were pretreated with or without Z-ATAD-FMK (ZAF), they were co-cultured with 5 × 105 TgCtwh3 or RH tachyzoites for 24 h. The presented figures are from a representative study and the graphics represent the mean and SD on different assays (n = 3). The C17.2 cells without the co-culture of tachyzoites or only pretreated with ZAF were used as controls. TgCtwh3 or RH + ZAF stands for the C17.2 cells pretreated with Z-ATAD-FMK, and then co-cultured with either TgCtwh3 or RH tachyzoites. The experiments were repeated three times. # P < 0.05 vs. control; *P < 0.05 vs. TgCtwh3 co-cultured group; & P < 0.05 vs. RH co-cultured group.