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. Author manuscript; available in PMC: 2016 Mar 24.
Published in final edited form as: Chem Eng Sci. 2014 Sep 16;125:32–57. doi: 10.1016/j.ces.2014.08.061

Fig. 7.

Fig. 7

Multicompartmental particles for combined imagine and siRNA delivery. (a) Bicompartmental particles illustrating different compartments with complimentary functions-imaging and siRNA delivery. (b) Fluorescent image of bicompartmental particles with blue fluorescent PLGA imaging compartment and a composite PLGA/crosslinked PEI compartment loaded with rhodamine-labeled siRNA. (c) siRNA release kinetics. (d) In vitro particles incubation experiments with MDA-MB-231/GFP breast cancer cells. Control: without treatment. PLGA/PEI+siRNA: particles and soluble siRNA. PLGA/PEI-siRNA: siRNA-loaded particles. Scale bar = 50 μm (reprinted from Misra et al., 2012. Copyright 2012 John Wiley & Sons, Inc.)