Table 1.
Selected nuclear receptors, their feed-forward regulatory partners, and examples of (putative) feed-forward gene targets highlighted in this review.
| Primary transcription factor (nuclear receptor)
|
Secondary transcription factor/alternative name
|
Feed-forward target gene(s)
|
|---|---|---|
| [Factor X] | [Factor Y] | [Gene Z] |
| PR | KLF9/BTEB1 | SLP1, DKK1, PRC1, UHRF1, IGFBP1, FAM167A |
| PR | SOX17/VUR3 | Ihh, Areg, SCGB1A1 |
| ERα | FOXA1/HNF3A | TFF1 |
| ERα | NRIP1/RIP140 | BCAS4, IRX4, GUSB, MUC1 |
| ERα | GREB1 | CXCL12, TRIM5 |
| AR | NKX3-1/NKX3A | RAB3B, RAB36, RAB20 |
| PPARγ | TLE3/GRG3 | Ap2, Cd36, Aqp7, Agpat2, Lpl |
| GR | KLF15/KKLF | AASS, PRODH, MT2A |