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. 2014 Oct 22;5(23):12203–12217. doi: 10.18632/oncotarget.2622

Figure 3. CD151 ablation enhances ovarian tumor growth and ascites production.

Figure 3

A Ectopic analyses of ovarian tumor growth. The back flanks of nude mice were subcutaneously injected with control and CD151-ablated OVCAR-5 cells respectively and subsequently measured for tumor appearance and growth over the indicated periods of (n =10). B Kaplan-Meier survival curve. Equal numbers of immuno-deficient mice were given an intra-peritoneal injection of OVCAR-5 cells with or without CD151 ablation (n = 10). C H & E stained sections of ovarian tumors derived from subcutaneously injected OVCAR-5 cells. a, c: control b, d: CD151 knockdown. Scale bar: 50 μm.