Table 2. Clinicopathologic and biologic factors affecting survival rate.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Variable | RR | 95% CI | P value | RR | 95% CI | P value |
| Age at diagnosis > 1.5 year versus ≤ 1.5 year | 4.098 | 1.938 – 8.662 | 0.001 | 1.242 | 0.459 – 3.357 | 0.670 |
| Clinical stage Advanced (3 & 4) versus early (1, 2 and 4S) | 13.328 | 4.146 – 42.842 | < 0.001 | 5.113 | 1.314 – 19.894 | 0.019 |
| MYCN Amplified versus non-amplified | 3.457 | 2.048 – 5.834 | < 0.001 | 2.034 | 1.135 – 3.645 | 0.017 |
| GALNT2 expression Negative versus positive | 4.320 | 2.265 – 8.239 | < 0.001 | 2.495 | 1.248 – 4.987 | 0.010 |
| INPC histology Unfavorable versus favorable | 3.720 | 2.115 – 6.543 | < 0.001 | 2.220 | 1.193 – 4.133 | 0.012 |
| Primary tumor site Adrenal versus non-adrenal | 1.299 | 0.764 – 2.211 | 0.334 | ND | ND | ND |
Abbreviations: INPC, International Neuroblastoma Pathology Classification; RR, risk ratio; 95% CI, 95% confidence interval; ND, not done.