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. 2014 Dec 2;5(23):12331–12345. doi: 10.18632/oncotarget.2589

Figure 2. Tg-mediated ER stress did not alter anti-tumor effector T cells.

Figure 2

(A-B), at 4 weeks after tumor challenge, the percentage and absolute number of CD8+ T cells in the spleen was assessed (n = 6). (C) percentages of Ly6C+ CD8+ T cells in the splenocytes of HER2/CT26 tumor-bearing mice. (D-E) specific lysis of hP63 (TYLPTNASL) peptide-loaded CFSEhigh target cells was estimated by in vivo CTL from the spleen and lymph node of HER2/CT26 tumor-bearing mice (n = 6). (F-G) the percentage and absolute number of CD4+ T cells in the spleen of HER2/CT26-bearing mice (n = 7). Graphs show mean ±SEM. ns, not significant, **p < 0.01; ***p < 0.001 compared with matched control group using the Student's t-test.