Table I.

Mutations induced by 8-OH-G containing c-Ha-ras genes transfected into NIH3T3 cells

Position of 8-OH-G
34		35		181		35
G*→Ta	14	G*→T	22	G*→T	35	G*→T	8
G*→A	1	G*→A	8	G*→A	0b	G*→A	3
G*→C	0	G*→C	1	G*→C	0b	G*→C	1
3′-G→T	0	5′-G→T	4	5′-T→A	1	5′-G→T	1
3′-G→A	0	5′-G→A	5	5′-T→C	4	5′-G→A	1
3′-G→C	0	5′-G→C	2	5′-T→G	0b	5′-G→C	0
total mutants	15	total mutants	42	total mutants	40	total mutants	14

^aG* represents 8-OH-G.

^bMutations at this position do not activate the c-Ha-ras gene.