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. 2006 May;82(4):155–164. doi: 10.2183/pjab.82.155

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© 2006 The Japan Academy

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figs. 4 and 5. — Scanning electron micrographs showing the Space of Disse and spines (arrows) of HSCs of the rat liver. Spines project from lateral edges of the subendothelial processes (SEP) course obliquely through the Space of Disse and contact with hepatocytes. BC: bile canaliculus; SL: sinusoidal lumen. × 8,000. Fig. 4 inset: A transmission electron micrograph of a longitudinal section of the spine which extends from the subendothelial process (asterisk). The spine, crossing the Space of Disse, adheres to both an endothelial cell (E) (arrowhead) and a hepatocyte (arrow). × 24,000 (Fig. 5 from ref. 62, Reprinted by permission).