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. Author manuscript; available in PMC: 2015 Feb 10.
Published in final edited form as: J Bone Miner Res. 2014 Sep;29(9):1970–1980. doi: 10.1002/jbmr.2223

Figure 5. Woven Bone Formation Is Impaired by Anti-Angiogenic Nanoparticles.

Figure 5

Woven bone volume and BMD were quantified using microCT measurements at day 7 and 14 following WBF loading. A) At day 7, nanoparticle treatment resulted in significantly less woven bone volume. B) At day 14, nanoparticle treatment for either 1 or 2 weeks did not result in any significant differences in woven bone volume. C) At day 7, there was no significant difference in woven bone BMD between nanoparticle and vehicle treated groups. D) At day 14, there was a significant and dose-dependent difference in woven bone BMD between nanoparticle and vehicle treated groups. * p < 0.05 vs. Vehicle.