Table 1.

Patient characteristics

Patient sample	ALL5	ALL6	ALL10	ALL12	ALL16	ALL17	ALL18	ALL19	ALL20	ALL 21
Age (years.months)	14.5	5.0	15.6	3.4	2.8	3.2	6.5	7.5	7.4	11.7
Sex	Female	Female	Female	Female	Male	Male	Male	Male	Male	Male
Sample from relapse	No	Yes	No	No	No	No	No	No	No	No
Immunophenotype	Common-B	Common-B	Common-B	Pre-B	Pre-B	Pre-B	Pre-B	Pre-B	Pre-B	Pre-B
Cytogenetics	t(9;22)	Normal karyotype	t(12;21)t(5;17)	t(12;21)(p13;q22)	47 ~ 48,XY,+X,i(21)(q10),+ i(21)(q10),[cp9]/46,XY[1]	46 XY, - 21c	t(12,21)	44, X,-Y,t(4;14) (q25;q32	46,XY,t(1;19)(q(23;p13)[2]/46,XY[23]	t(12;21)(p13;q22)
Residual disease at day 15	42 × 10-2	Not performed	30 × 10-2	1.1 × 10-2	3.2 × 10-3	8.9 × 10-3	8 × 10-3	No MRD	5 x 10-3	No MRD
Residual disease at day 29	27 × 10-2	No MRD	7.3 × 10-3	3 × 10-4	No MRD	9 × 10-4	5 × 10-4	No MRD	No MRD	No MRD

MRD: minimal residual disease.