Table 4. Summary of Variant QC from the Follow-up Genotyping.

	Sequence	GWAS hit	Complete
	Variant		Dataset
Selected from sequence data	56	21	77
Failed to genotype	5	2	7
Failed to validate, monomorphic	2	0	2
Dropped due to low marker efficiency	0	2	2
Dropped due to multiallelic variant	1	0	1
Available for analysis	48	17	65

Sequence variant = variant identified from whole-exome sequence data. GWAS hit = SNP implicated by two recent meta-analyses [16,18]. Complete dataset = all variants and markers genotyped in three Sequenom pools and two TaqMan assays.