Table 4.
Relationship between maternal HBV DNA status, PBMC HBV infection and newborn infant HBV infection
| Maternal HBV DNA status | Newborn infant HBV infection | OR | 95% CI | |
|---|---|---|---|---|
| Yes | No | |||
| Serum HBV DNA/PBMC | N (%) | N (%) | ||
| -/- | 35/123 (28.5) | 88/123 (71.5) | 1.000 | - |
| +/- | 40/89 (44.9) | 49/89 (55.1) | 2.05 | 1.16-3.64 |
| -/+ | 34/52 (65.4) | 18/52 (34.6) | 4.75 | 2.38-9.49 |
| +/+ | 33/48 (68.7) | 15/48 (31.3) | 5.53 | 2.68-11.42 |
Test of homogeneity χ2=33.07, P=0.0000; Score test for trend of odds χ2=18.78, P=0.0000;
Note: HBV DNA positive and HBV DNA negative denote mothers who were positive or negative for HBV DNA in serum, respectively; PBMC HBV DNA (+) denotes mothers who were HBV-infected in PBMCs; PBMC HBV DNA (-) denotes mothers who did not have HBV infection in PBMCs.
Abbreviations: OR, odds ratio; CI, confidence interval; PBMC, peripheral blood mononuclear cell; HBV, hepatitis B virus.