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. 2015 Feb 1;4:41. doi: 10.1186/s40064-015-0798-9

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© Oda and Minata; licensee Springer. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Changes in inflammation and disease activity: A) CRP & ESR, B) MMP-3, Clinical course and the treatment showed that the inflammation and disease activity were improved after terminating of the MTX and ADA and administrating the steroid pulse treatment.