Table 1.
Correlation of fibroblast growth factor receptor 4 expression with clinicopathological characteristics n (%)
| Clinicopathological characteristics | n | FGFR4 positive | FGFR4 negative | χ2 | P value |
| 175 | 77 (44.00) | 98 (56.00) | |||
| Gender | 0.1140 | 0.8663 | |||
| Male | 125 | 56 (44.8) | 69 (55.20) | ||
| Female | 50 | 21 (42.00) | 29 (58.00) | ||
| Age (yr) | 0.9211 | 1.0000 | |||
| < 60 | 72 | 32 (44.44) | 40 (55.56) | ||
| ≥ 60 | 103 | 45 (43.69) | 58 (56.31) | ||
| Tumor size | 0.1400 | 0.1518 | |||
| ≤ 3 cm | 60 | 31 (51.67) | 29 (48.33) | ||
| > 3 cm | 115 | 46 (40.00) | 69 (60.00) | ||
| Tumor location | 1.3942 | 0.4980 | |||
| U | 32 | 17 (53.13) | 15 (46.88) | ||
| M | 71 | 29 (40.85) | 42 (59.15) | ||
| L | 72 | 31 (43.06) | 41 (56.94) | ||
| Tumor differentiation | 0.2191 | 0.1129 | |||
| Poor | 76 | 29 (38.16) | 47 (61.84) | ||
| Well | 99 | 48 (48.48) | 51 (51.52) | ||
| Macroscopic type | |||||
| EGC | 21 | 8 (38.10) | 13 (61.90) | 9.3842 | 0.0522 |
| I | 9 | 3 (33.33) | 6 (66.67) | ||
| II | 5 | 3 (60.00) | 2 (40.00) | ||
| III | 127 | 62 (48.82) | 65 (51.18) | ||
| IV | 13 | 1 (7.69) | 12 (92.31) | ||
| TNM stages | 0.3499 | 0.9504 | |||
| I | 37 | 15 (40.54) | 22 (59.46) | ||
| II | 45 | 21 (46.67) | 24 (53.33) | ||
| III | 69 | 30 (43.48) | 39 (56.52) | ||
| IV | 24 | 11 (45.83) | 13 (54.17) | ||
| T | 0.9523 | 0.8128 | |||
| 1 | 21 | 8 (38.10) | 13 (61.90) | ||
| 2 | 29 | 14 (48.28) | 15 (51.72) | ||
| 3 | 64 | 30 (46.88) | 34 (53.13) | ||
| 4 | 61 | 25 (40.98) | 36 (59.02) | ||
| N | 1.8160 | 0.6115 | |||
| 0 | 55 | 27 (49.09) | 28 (50.91) | ||
| 1 | 32 | 11 (34.38) | 21 (65.63) | ||
| 2 | 24 | 11 (45.83) | 13 (54.17) | ||
| 3 | 64 | 28 (43.75) | 36 (56.25) | ||
| M | 0.0379 | 1.0000 | |||
| 0 | 151 | 66 (43.71) | 85 (56.29) | ||
| 1 | 24 | 11 (45.83) | 13 (54.17) | ||
| Neural invasion | 0.7576 | 0.5146 | |||
| Yes | 25 | 9 (36.00) | 16 (64.00) | ||
| No | 150 | 68 (45.33) | 82 (54.67) | ||
| Vascular invasion | 0.4473 | 0.2356 | |||
| Yes | 35 | 13 (37.14) | 22 (62.86) | ||
| No | 140 | 64 (45.71) | 76 (54.29) | ||
| P53 | 3.0941 | 0.3773 | |||
| 0 | 72 | 37 (51.39) | 35 (48.61) | ||
| 1 | 43 | 16 (37.21) | 27 (62.79) | ||
| 2 | 20 | 7 (35.00) | 13 (65.00) | ||
| 3 | 40 | 17 (42.50) | 23 (57.50) | ||
| P27 | 0.9924 | 0.8031 | |||
| 0 | 87 | 37 (42.53) | 50 (57.47) | ||
| 1 | 72 | 34 (47.22) | 38 (52.78) | ||
| 2 | 12 | 4 (33.33) | 8 (66.67) | ||
| 3 | 4 | 2 (50.00) | 2 (50.00) | ||
| Topo IIα | 9.4760 | 0.0236 | |||
| 0 | 83 | 29 (34.94) | 54 (65.06) | ||
| 1 | 66 | 31 (46.97) | 35 (53.03) | ||
| 2 | 25 | 14 (60.87) | 9 (39.13) | ||
| 3 | 3 | 3 (100) | 0 (0) |
FGFR4: Fibroblast growth factor receptor 4; TNM: Tumor-node-metastasis.