Table 2.
Model | HIV-infected |
Uninfected Controls (N = 941) | |
---|---|---|---|
Undetectable HIVRNA (N = 698*) | Detectable HIVRNA (N =1946) | ||
Unadjusted AMH level** | 0.56 (0.48, 0.65) | 0.37 (0.33, 0.42) | 0.63 (0.53, 0.74) |
% Estimate (95%CI)‡ | % Estimate (95%CI)‡ | ||
Adjusted for age | −15.7 (−25.3, −4.8), p=0.0058 | −25.6 (−33.5, −16.8), p<.0001 | Reference |
Multivariable-adjusted§ | 27.7 (10.4, 47.9), p=0.0010 | 31.2 (13.5, 51.6), p=0.0002 | Reference |
sample size given at baseline. The numbers within each group may change during follow-up as a result of increases or decreases in HIVRNA levels, as well as seroconversion among participants who were uninfected at baseline.
estimated geometric mean AMH level (ng/mL) at age 40, with 95%CI.
AMH is log-transformed; results are back-transformed to produce estimated percentage differences in AMH attributable to each factor. Estimates are from mixed models for left-censored repeated measures.
Adjusted for age, race, current smoking, current hormonal contraceptive use, history of amenorrhea, history of weight loss, current CD4 count, nadir CD4 count, nadir CD8 count, and nadir T lymphocyte count.