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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Math Biosci. 2014 Dec 9;261:48–61. doi: 10.1016/j.mbs.2014.11.004

Figure 6. Changes in model predictions with changes in parameters.

Figure 6

The indicated parameter values were increased by 0.1 h−1. The rate equations were solved numerically with all other rate constants at their original values. (A) Presenilin-1 mutation carrier with plaques validated by PET PIB scans, (B) Non-carrier without plaques. The observed trends help to visualize the results of the sensitivity analysis shown in Figure 4.