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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Exp Neurol. 2014 Dec 4;264:67–81. doi: 10.1016/j.expneurol.2014.11.014

Figure 10.

Figure 10

NPC transplantation increased levels of endogenous DG neurogenesis. Representative images of BrdU/NeuN double-labeled cells in the ipsilateral DG from a TBI/vehicle (A) and a TBI/MNTS1 (B) animal 6 weeks post TBI. Green, BrdU; red, NeuN. C) Nonbiased stereological assessment of double-labeled cells showed that transplantation of GFP-control NPCs increased levels of BrdU/NeuN-positive cells in the sham group relative to sham/vehicle animals. Injured animals transplanted with MNTS1-expressing NPCs exhibited a greater magnitude of hippocampal neurogenesis compared to injured and uninjured vehicle-injected control animals (*p < 0.05; **p < 0.01).