Table 1.
Characteristics | Total (%) (N=14 041) | Early Aspirin User (%) (N=12 260) | Early Aspirin Non‐User (%) (N=1781) | P Value |
---|---|---|---|---|
Demographic | ||||
Age, y | <0.001 | |||
<55 | 22.1 | 23.0 | 16.3 | |
55 to 64 | 23.6 | 24.0 | 20.9 | |
65 to 74 | 30.1 | 29.9 | 31.0 | |
≥75 | 24.2 | 23.1 | 31.8 | |
Gender | <0.001 | |||
Male | 69.9 | 70.7 | 64.4 | |
Female | 30.1 | 29.3 | 35.7 | |
Cardiac risk factors | ||||
Prior hypertension | 49.5 | 49.9 | 46.8 | 0.015 |
Prior diabetes | 17.4 | 17.3 | 18.1 | 0.388 |
Current smoker | 34.7 | 35.8 | 27.3 | <0.001 |
Medical histories | ||||
Ischemic stroke | 10.0 | 9.7 | 12.0 | 0.003 |
Myocardial infarction | 10.8 | 10.9 | 10.3 | 0.460 |
Primary PCI | 1.9 | 2.0 | 1.3 | 0.059 |
Clinical characteristics at admission | ||||
Chest discomfort | 91.9 | 93.5 | 81.5 | <0.001 |
Cardiac arrest | 1.0 | 0.8 | 2.0 | <0.001 |
Cardiogenic shock | 4.2 | 4.0 | 5.9 | <0.001 |
Blood pressure mmHg | 0.080 | |||
SBP<180 and DBP<110 | 91.6 | 91.8 | 90.6 | |
SBP≥180 or DBP≥110 | 8.4 | 8.2 | 9.4 | |
AMI type | <0.001 | |||
STEMI | 85.4 | 86.1 | 80.6 | |
NSTEMI | 14.6 | 13.9 | 19.4 | |
Reperfusion therapy | 0.027 | |||
No reperfusion | 69.3 | 67.4 | 82.5 | |
Fibrinolytic therapy | 20.3 | 21.4 | 12.4 | |
Primary PCI | 10.4 | 11.2 | 5.2 | |
Hospital characteristics | ||||
Teaching hospital | 80.8 | 80.7 | 75.5 | <0.001 |
PCI‐capable hospital | 60.7 | 62.2 | 50.3 | <0.001 |
Economic geographic region | 0.915 | |||
Eastern | 59.2 | 58.6 | 62.7 | |
Center | 21.3 | 21.5 | 19.4 | |
Western | 19.6 | 19.8 | 17.9 | |
Urban/Rural | <0.001 | |||
Urban | 61.1 | 62.3 | 52.8 | |
Rural | 38.9 | 37.7 | 47.2 | |
Year | <0.001 | |||
2001 | 15.0 | 13.6 | 24.9 | |
2006 | 28.3 | 28.1 | 29.6 | |
2011 | 56.7 | 58.3 | 45.5 |
AMI indicates acute myocardial infarction; DBP, diastolic blood pressure; NSTEMI, non‐ST‐segment elevation myocardial infarction; PCI, percutaneous coronary intervention; SBP, systolic blood pressure; STEMI, ST‐segment elevation myocardial infarction.