Table 9.

Effects of Admission Time on Primary Outcomes (mRS=5 to 6) Among Acute Stroke Patients by Japan Coma Scale

Japan Coma Scale	Admission Time	Total Population		IS		SAH		ICH
		Adjusted OR* (95% CI)	P Value*	Adjusted OR* (95% CI)	P Value*	Adjusted OR* (95% CI)	P Value*	Adjusted OR* (95% CI)	P Value*
0	Working‐hours	1.00 (reference)	—	1.00 (reference)	—	1.00 (reference)	—	1.00 (reference)	—
	Off‐hour	1.45 (1.33 to 1.58)	<0.001	1.07 (0.87 to 1.33)	0.515	0.87 (0.48 to 1.56)	0.633	1.29 (0.86 to 1.93)	0.220
	Nighttime	1.45 (1.33 to 1.58)	<0.001	1.59 (1.11 to 2.29)	0.011	0.83 (0.34 to 1.99)	0.672	2.87 (1.66 to 4.98)	<0.001
1‐digit	Working‐hours	1.00 (reference)	—	1.00 (reference)	—	1.00 (reference)	—	1.00 (reference)	—
	Off‐hour	1.20 (1.09 to 1.33)	<0.001	1.20 (1.07 to 1.36)	0.003	1.00 (0.64 to 1.55)	0.998	1.21 (1.00 to 1.45)	0.044
	Nighttime	1.06 (0.89 to 1.26)	0.536	0.98 (0.78 to 1.23)	0.856	1.28 (0.71 to 2.31)	0.416	1.01 (0.73 to 1.41)	0.941
2‐digit	Working‐hours	1.00 (reference)	—	1.00 (reference)	—	1.00 (reference)	—	1.00 (reference)	—
	Off‐hour	1.08 (0.94 to 1.24)	0.295	1.03 (0.85 to 1.25)	0.770	0.93 (0.60 to 1.44)	0.751	1.18 (0.93 to 1.48)	0.170
	Nighttime	0.91 (0.73 to 1.14)	0.406	0.89 (0.63 to 1.25)	0.498	1.56 (0.84 to 2.88)	0.160	0.81 (0.57 to 1.16)	0.250
3‐digit	Working‐hours	1.00 (reference)	—	1.00 (reference)	—	1.00 (reference)	—	1.00 (reference)	—
	Off‐hour	0.81 (0.69 to 0.95)	0.008	0.65 (0.48 to 0.88)	0.006	0.81 (0.60 to 1.10)	0.169	0.89 (0.70 to 1.13)	0.325
	Nighttime	0.70 (0.57 to 0.86)	0.001	0.50 (0.31 to 0.81)	0.005	0.77 (0.51 to 1.15)	0.196	0.67 (0.49 to 0.90)	0.009

ICH indicates intracerebral hemorrhage; IS, ischemic stroke; mRS, modified Rankin Scale; SAH, subarachnoid hemorrhage.

^*Off‐hour and nighttime were compared with working‐hours.

^*Adjusted for age, sex, hypertension, diabetes mellitus, hyperlipidemia, and hospital volume.