Table 3.
Variable | Clopidogrel‐Naïve | On Clopidogrel | ||
---|---|---|---|---|
F | P Value | F | P Value | |
Sex | 46 | <0.0001 | 43 | <0.0001 |
Race | 4.3 | 0.04 | 5.4 | 0.02 |
Diabetes mellitus | 23.2 | <0.0001 | 15.2 | <0.0001 |
Hypertension | 5.6 | 0.02 | 5.1 | 0.02 |
History of smoking | 0.4 | 0.7 | 0.3 | 0.8 |
Hyperlipidemia | 0.1 | 0.8 | 0 | 1 |
Significant CAD* | 0.7 | 0.5 | 0.1 | 0.9 |
Family history of CAD | 1.4 | 0.3 | 0.1 | 0.9 |
History of PCI | 0.8 | 0.4 | 0.2 | 0.7 |
History of CABG | 0.02 | 0.9 | 0.2 | 0.6 |
History of MI | 0.7 | 0.4 | 0.4 | 0.5 |
History of stroke | 0.1 | 0.8 | 0 | 1 |
PAD | 1.1 | 0.3 | 0.4 | 0.5 |
Chronic renal insufficiency* | 3.5 | 0.07 | 1.3 | 0.2 |
Beta blockers | 0.9 | 0.4 | 5.6 | 0.02 |
Statins | 1 | 0.4 | 0.4 | 0.8 |
ACE inhibitors or ARBs | 0.4 | 0.6 | 1.3 | 0.25 |
Calcium blockers | 8.6 | 0.001 | 2.5 | 0.08 |
PPIs | 0.9 | 0.5 | 0.5 | 0.8 |
Nitrates | 0.7 | 0.5 | 0.1 | 0.9 |
Analyses performed by multivariate analysis of variance. ACE indicates angiotensin‐converting enzyme; ARB, angiotensin II receptor blocker; CABG, coronary artery bypass grafting; CAD, coronary artery disease; MI, myocardial infarction; PAD, peripheral arterial disease; PCI, percutaneous coronary intervention; PPI, proton pump inhibitor.
At least 1 coronary artery with ≥50% stenosis according to current angiogram.
†Creatinine ≥1.5 mg/dL.