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. Author manuscript; available in PMC: 2016 Feb 15.
Published in final edited form as: J Immunol. 2015 Jan 16;194(4):1788–1795. doi: 10.4049/jimmunol.1203239

Figure 1. β-Defensin 1 protects against early mucosal infection and controls systemic dissemination with Candida albicans.

Figure 1

Quantitative fungal burdens of (A) Tongues, (B) Esophagus, (C) Stomach, and (D) Ileum of WT and DEFB1−/− mice after oral infection for 3, 7, 14 and 21 d with Candida. (E) Clinical severity of infection was determined by gross examination of tongues. (F) Systemic dissemination was determined by kidney fungal loads. All bars represent an N ≥ 5 mice pooled from a minimum of two experiments. (Data shown are means ± SEM; ***P < 0.001, ** P < 0.01, * P < 0.05)