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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Environ Toxicol Pharmacol. 2014 Nov 1;39(1):114–124. doi: 10.1016/j.etap.2014.10.017

Fig. 4. CYP1A1 and CYP4B1 production from MCF10A cells in response to density or ligands known to activate HRE and XRE.

Fig. 4

Cells were cultured in low density (LD) or high density collagen gels for 24 h and assessed for P450 enzyme production (A-D) or cultured in LD collagen gels +/− vehicle control (V), 100 μM DFOM (D) or tranilast (T) for 24 h (E-H). Representative immunoblots are displayed (A,B,E,F) and the mean band densitometry relative to the GAPDH and normalized to the control are charted (C,D,G,H) +/− SEM, N>4 *p<0.05 vs respective control.