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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: J Autoimmun. 2014 Dec 29;57:42–52. doi: 10.1016/j.jaut.2014.11.007

Fig. 8.

Fig. 8

Delayed treatment with GW2580. Treatment with GW2580 starting on day 5, rather than day 0, remains effective in attenuating the development of kidney dysfunction in NTS challenged mice (A) Experimental time line. (B) Proteinuria was significantly reduced in GW2580 treated mice, as determined by the urinary albumin to creatinine ratio. Results are shown as the values normalized to control mice. (C) Serum creatinine does not rise in response to the nephrotoxic challenge in GW2580 treated mice. Results shown are from one experiment (control mice, n = 4; NTS/GW2580 mice, n = 8; NTS/PBS mice, n = 8), which is representative of the two experiments performed.