Table 1.
Baseline demographic characteristics of case and control groups in the Linxian Nutrition Intervention Trials cohort
| Controls (N=1018) | Case (N=496)
|
||||
|---|---|---|---|---|---|
| Liver cancer incidence (n=220) | P value | Chronic liver disease death (n=276) | P value | ||
| Age (yr), Median (IQR) | 55.0 (50.0, 61.0) | 55.0 (49.0, 61.0) | 0.72 | 55.0 (49.0, 61.0) | 0.83 |
| Sex (%) | |||||
| Women | 468 (46.0) | 88 (40.0) | 0.11 | 137 (49.6) | 0.28 |
| Men | 550 (54.0) | 132 (60.0) | 139 (50.4) | ||
| Smoking (%) | |||||
| No | 657 (64.6) | 134 (60.9) | 0.30 | 181 (65.8) | 0.71 |
| Yes | 360 (35.4) | 86 (39.1) | 94 (34.2) | ||
| Alcohol drinking | |||||
| No | 776 (76.3) | 165 (75.0) | 0.68 | 213 (77.5) | 0.69 |
| Yes | 241 (23.7) | 55 (25.0) | 62 (22.5) | ||
| BMI (kg/m2), Median (IQR) | 21.5 (20.2, 23.0) | 21.8 (20.1, 23.0) | 0.75 | 21.6 (20.4, 23.3) | 0.12 |
| HBsAg (%) | |||||
| No | 962 (94.6) | 168 (76.4) | <0.001 | 193 (69.9) | <0.001 |
| Yes | 55 (5.4) | 52 (23.6) | 83 (30.1) | ||
| HBcAg (%) | |||||
| No | 422 (41.5) | 67 (30.5) | 0.002 | 82 (29.7) | <0.001 |
| Yes | 595 (58.5) | 153(69.5) | 194 (70.3) | ||
| HCsAg (%) | |||||
| No | 946 (93.0) | 196 (89.1) | 0.047 | 229 (83.0) | <0.001 |
| Yes | 71 (7.0) | 24 (10.9) | 47 (17.0) | ||
| C-reactive protein(mg/L), Median (IQR) | 0.34(0.15, 0.84) | 0.47(0.18, 1.16) | 0.003 | 0.54(0.21, 1.36) | <0.001 |