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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2014 Dec 3;24(2):435–441. doi: 10.1158/1055-9965.EPI-14-1178

Table 1.

Composition of the Breast Cancer Reference Set (n=831)

Sample Type Screening (PRoBE 1) Diagnostic (PRoBE 2)
Normal 176 1001
Benign w/out atypia 72 159
Benign w/atypia 11 52
Carcinoma in situ 15 40
Invasive Carcinoma 35 1543
Cancer (pre-clinical2) 17 0
1

Women with normal mammograms not referred for biopsy collected at the same institutions as the diagnostic samples

2

Women with normal screening mammograms later diagnosed with cancer including DCIS, invasive breast cancer, and cancers of other organs.

3

These numbers are for plasma. There is one more invasive cancer (n=155) that has serum deposited.