Table 1.

Mutations in ion channel-coding genes linked to ADNFLE.

Gene	Protein/subunit	Mutation	Reference
CHRNA4	nAChR (α4)	S248F	Steinlein et al., 1995
		S252L	Hirose et al., 1999
		776ins3	Steinlein et al., 1997
		T265I	Leniger et al., 2003
CHRNB2	nAChR (β2)	V287L	De Fusco et al., 2000
		V287M	Phillips et al., 2001
		I312M	Bertrand et al., 2005
		L301V	Hoda et al., 2008
		V308A
CHRNA2	nAChR (α2)	I279N	Aridon et al., 2006
KCNT1	Kca4.1	M896I	Heron et al., 2012
		R398Q
		Y79 6H
		R928C