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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Immunol Cell Biol. 2014 Sep 23;93(2):120–125. doi: 10.1038/icb.2014.78

Figure 1.

Figure 1

FoxO3 regulates the expansion of CD8+ T cells. A–C 500 OT-I CD45.1 FoxO3−/− and 500 OT-I CD45.2 cells were co-injected into WT (CD45.1/2) mice one day before immunization. The mice were infected with 1×106 vaccinia-OVA or with 5×106 Actm-OVAkb−/− splenocytes. In A and B the responses were measured in the blood at day 7. In C the ratio of OT-I was measured at day 7 in different organs. Data are representative of groups of 4 to 5 mice and represents the most representative result of 2 to 3 independent experiments.