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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Twin Res Hum Genet. 2015 Jan 13;18(1):19–27. doi: 10.1017/thg.2014.81

Table 3.

Ordinalized data simulation: Percent of simulated LRT statistics under the null hypothesis exceeding critical value for pairs of nested models based on 2000 replicates of N=1000.

% Type I error rates

DGM LRT df Ordinalized on M Ordinalized on P
Model for HA Model for H0 Condition of H0 10 5 1 10 5 1
Cholesky with G×M (3) NL main effects with G×M (4) Large β2 4 4.9 2.4 0.3 3.0 1.0 0.2
Small β2 4 4.4 1.8 0.1 1.9 0.7 0.2
NL main effects (4*) Large β2 7 5.9 2.6 0.6 4.4 2.2 .25
Small β2 7 5.7 2.5 0.5 15.4 8.8 2.1
Choleskya (2) high rAM 6 7.2 3.4 0.7 22.9 13.4 3.2
low rAM 6 8.2 3.9 0.7 35.3 21.4 6.6

NL main effects with G×M (4) NL main effects (4*) Large β2 3 9.3 4.8 0.8 8.8 3.6 0.9
Small β2 3 8.0 4.1 1.0 31.9 20.5 6.9

NL main effects (4*) Lin main effectsa (4†) 1 10.8 4.6 1.4 17.6 10.3 2.3

Cholesky (2) Lin Main effects (4†) 2 8.3 4.4 0.7 9.4 4.8 0.7

Note: P refers to a phenotype of interest, M refers to a putative moderator. LRT refers to the likelihood ratio test.

a

DGM does not contain G×M effects.