Table 2.
Results of Infection-Related Investigations for Indigenous Adults With Bronchiectasis and Their Matched Controlsa
| Cases (n = 36) | Controls (n = 36) | P Value | |
|---|---|---|---|
| HTLV-1 Studies | |||
| WB positive (n, %) | 25 (69.4) | 15 (41.7) | .018 |
| PVL (per 100 PBL) (median, IQR) | 0.319 (0.007, 0.749) | 0.003 (0.000, 0.051) | .007 |
| Ab titer (log units) (mean ± SE) | 8.53 (6.93, 9.92) | 5.55 (4.85, 7.62) | .0035 |
| Strongyloides Serologyb (n, %) | |||
| Positive | 15 (41.7) | 4 (16.0) | <.001 |
| Negative | 11 (30.6) | 20 (80.0) | |
| Equivocal | 10 (27.8) | 1 (4.0) | |
| Sputum Cultures (median, IQR) | 3 (2, 6)d | 3 (2,7) | .814 |
| Haemophilus influenzae | 1 (0, 3)d | 0 (0, 1) | .058 |
| Number of pathogens | 2.7 (3.9)d | 1.2 (2.3) | .023 |
| Eosinophiliac (n, %) | 22 (61.1) | 10 (27.8) | .004 |
Abbreviations: Ab, HTLV-1 antibody titer; HTLV-1, human T-lymphotropic virus type 1; IQR, interquartile range; PBL, peripheral blood lymphocytes; PVL, HTLV-1c proviral load; SE, standard error; WB, Western blot.
a Continuous variables are summarized using mean and SE or median and IQR as appropriate.
b Strongyloides serology performed for 36 cases and 25 controls.
c Eosinophils >0.7 × 109/L for >12 months.
d Pathogens isolated from sputum specimens cultured prior to diagnosis with bronchiectasis.