Table 1.

Characteristics of Patients With Presumed Candida Pneumonia, Medical History, and Results of Examinations

	Case 1	Case 2	Case 3	Case 4	Case 5
Age	84	58	74	55	70
Sex	Female	Male	Male	Male	Male
Admission	Respiratory insufficiency, general malaise, watery diarrhea, loss of appetite, vomiting	General malaise	Bacterial meningitis	Respiratory insufficiency	Myocardial infarction
Medical history	Radical abdominal hysterectomy for endometrial carcinoma	Myelodysplastic syndrome, allogenic stem cell transplantation	Nonactive tuberculosis, urothelial carcinoma	Resection of brain metastasis, poorly differentiated adenocarcinoma	Coronary artery disease
Complicating factors	Zenker's diverticel, malnourished, nicotine abuse	Graft-versus-host disease, prednisolone and cyclosporine use	Perforated diverticulitis, dexamethasone medication	Necrotizing pancreatitis, dexamethasone medication	Aspiration
Radiology	X-ray: bilateral micronodular infiltrates	X-ray: infiltrate in right lung, pleural effusions	X-ray: bilateral upper quadrant infiltrates	CT thorax: bilateral infiltrative consolidations	X-ray: bilateral infiltrative consolidations
Microbiology	BAL: 6.2% intracellular yeasts 8×103 CFU/mL, Candida glabrata Sputum: C glabrata Zenkeŕs diverticel culture: C glabrata Blood: sterile Urine: sterile	BAL: 55% intracellular yeasts >105 CFU/mL Candida albicans Sputum: C albicans, Citrobacter freundii Blood: sterile Urine: sterile Central venous line: sterile	BAL: 0.4% intracellular yeasts 4×103 CFU/mL, C albicans 5 × 102 CFU/mL, C glabrata Sputum: C albicans Blood: sterile Urine: sterile Peritoneal fluid: C albicans, C glabrata Liquor PCR: Neisseria meningitidis	BAL: 7.4% intracellular yeasts 5.6 × 104 CFU/mL, C albicans Sputum: C albicans Blood: Streptococcus mitis Urine: sterile Abdominal fluid: sterile Central venous line: sterile	BAL: 0.6% intracellular yeasts 104 CFU/mL, C glabrata Sputum: pharyngeal flora Blood: sterile Urine: sterile
Antibiotics	Moxifloxacin, fluconazole	Piperacillin/tazobactam amphotericin B	Ceftriaxone, fluconazole	Levofloxacin amoxicillin/clavulanic acid fluconazol	Amoxicillin/clavulanic acid
Autopsy	None, patient survived	Lung tissue: Candida species, Enterobacter sakazakii	None, patient survived	Not permitted	Not permitted

Abbreviations: BAL, bronchoalveolar lavage; CT, computed tomography; PCR, polymerase chain reaction.