Table 2.
Multivariate Analysis of Death at Any Time During Treatment Among Culture-Confirmed Patients Who Died on Treatment vs Completed Treatment—California, 1994–2008
| Factor | aOR (95% CI) | Forest Plot of aOR and 95% CI |
|---|---|---|
 |
||
| Age | 1.06 (1.055–1.062) | |
| Male sex | 1.14 (1.03–1.26) | |
| Race/ethnicity | ||
| White non-Hispanic | Ref | |
| Black non-Hispanic | 1.19 (0.99–1.43) | |
| Hispanic | 1.20 (1.02–1.42) | |
| Asian/PI non-Hispanic | 1.08 (0.91–1.29) | |
| Drug resistance | ||
| Pandrug sensitive | Ref | |
| INH monoresistant | 0.90 (0.73–1.11) | |
| RIF monoresistant | 3.07 (1.69–5–57) | |
| Initial MDR | 2.96 (2.04–4.30) | |
| Acquired MDR | 4.67 (2.09–10.45) | |
| Other DR | 1.25 (1.02–1.54) | |
| Meningeal TB | 4.59 (3.40–6.20) | |
| HIV | 4.39 (3.68–5.24) | |
| Peritoneal TB | 3.36 (2.48–4.54) | |
| Private provider | 3.08 (2.75–3.44) | |
| Disseminated TB | 2.30 (1.82–2.91) | |
| Long-term care | 2.27 (1.89–2.73) | |
| Initial regimen <3 drugs | 2.07 (1.63–2.64) | |
| Injection drug use | 1.75 (1.37–2.23) | |
| Abnormal CXR, no cavities | 1.58 (1.32–1.90) | |
| Sputum smear positive | 1.52 (1.38–1.69) | |
| Pleural TB | 1.49 (1.33–1.68) | |
| DOT | 1.40 (1.26–1.56) | |
| US-born | 1.40 (1.21–1.62) | |
| Excess alcohol use | 1.33 (1.14–1.54) | |
| Incarceration | 0.50 (0.33–0.77) | |
| HIV and disseminated TB | 0.62 (0.43–0.91) | |
Abbreviations: aOR, adjusted odds ratio; CI, confidence interval; CXR, chest radiograph; DOT, directly observed therapy; DR, drug resistance; HIV, human immunodeficiency virus; INH, isoniazid; IQR, interquartile range; MDR, multidrug resistance; PI, Pacific Islander; RIF, rifampin; TB, tuberculosis; US, United States.