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. 2014 Dec 9;5(6):e01562-14. doi: 10.1128/mBio.01562-14

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Copyright © 2014 Qi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FIG 6 — Decreased transcriptional efficiency increases the average magnitude of deviation in transcript levels of essential genes in rpoB mutants relative to the levels in the ancestral strain. The graph shows the correlation between relative transcriptional efficiencies (mean ± SE; n = 3) and average magnitudes of deviation in relative transcript levels of essential genes in resistant mutants (mean ± SE; n = 15). Decreased relative transcriptional efficiency is associated with elevated average deviation in relative transcript levels of essential genes in rpoB mutants, as determined by linear regression (dashed line). The ancestral strain is shown in black, and the compensated mutant H531C in green. Q518R + E528D and H531Y + N573S mutants were omitted from the correlation analysis.