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(a) The frequency distributions of participants with IFN-γ-producing cells as measured by ELISPOT assay to individual HA proteins are shown as spot-forming units (SFU) per million PBMCs. (b) Individual PBMC IFN-γ responses for each HA protein or total response to any HA protein are plotted by ELISA cluster. Frequencies have been corrected for background IFN-γ production in unstimulated control cultures.
