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. 2009 Jul 8;2009(3):CD002759. doi: 10.1002/14651858.CD002759.pub2

Segal 2003.

Methods RCT 
 Method of randomisation: using a table of random numbers, which was stratified by study centers and intent of treatment (curative or palliative) 
 Assessor blinding: yes 
 Participant blinding: no 
 Loss to follow‐up: 8/82 in the PRT group; 12/73 in the control group 
 Intention‐to‐treat analysis: yes 
 Post‐program follow up: no
Participants Location: Canada 
 N = 155 (82 in PRT) 
 Sample: men with prostate cancer 
 Age: mean 68.2 years (SD = 7.9) 
 Inclusion criteria: had prostate cancer, would received androgen deprivation therapy for at least 3 months after recruitment, and the treating oncologist provided consent 
 Exclusion criteria: severe cardiac disease, uncontrolled hypertension, pain, unstable bone lesions, and residence more than 1 hr from the study center
Interventions PRT versus control 
 1. PRT 
 Type of Ex: 6UL/3LL 
 Equipment: not reported 
 Intensity: 60‐70% of 1 RM, increased 5 lb after 12 successful repetitions 
 Frequency: Ex3 
 Reps/Sets: 8‐12/2 
 Duration: 12 weeks 
 Setting: fitness center 
 Supervision: full 
 Adherence: 79% 
 2. Control Group: on a waiting list, offered the identical exercise advice and guideline as the exercise group after the study period
Outcomes Primary: Health‐related quality of life 
 Secondary: Muscle fatigue (Number of repetition) 
 Comments of adverse events: no
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear