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. 2009 Jul 8;2009(3):CD002759. doi: 10.1002/14651858.CD002759.pub2

Fiatarone 1994.

Methods RCT, factorial design (comparison of nutritional supplements versus placebo not considered here) 
 Method of randomisation: not reported 
 Assessor blinding: for some assessments, not for all 
 Participant blinding: no, but recreational activities offered to control group (? quantity) 
 Loss to follow‐up: 6 total (4 in PRT and control groups) 
 Intention‐to‐treat analysis: yes 
 Post‐program follow up: falls monitored median 1.53 years, max 4.11 years
Participants Location: USA 
 N = 51 in PRT vs control 
 Sample: residents of a long term care facility for older people 
 Age: mean 87.1 years (SE 0.6) 
 Inclusion criteria: residential status, age over 70 years, ability to walk 6m 
 Exclusion criteria: severe cognitive impairment; rapidly progressive or terminal illness, acute illness or unstable chronic illness; myocardial infarction; fracture of a lower extremity within the six months before the study; insulin dependent diabetes mellitus; on a weight‐loss diet or undergoing resistance training at the time of enrolment; tests of muscle strength revealed a musculoskeletal or cardiovascular abnormality
Interventions PRT versus control 
 1. PRT 
 Type of Ex: 2LL 
 Equipment: weight training machines 
 Intensity: high (80% of 1RM) 
 Frequency: Ex3 
 Reps/sets: 8/3 
 Program duration: 10 weeks 
 Setting: nursing home 
 Supervision: full 
 Adherence: 97% 
 2. Control Group: engaged in 3 activities of their choice offered by recreational therapy
Outcomes Strength (1RM) 
 Gait speed 
 Stair climbing power 
 Anthropometric measurements 
 Physical activity (leg monitors) 
 Comments on adverse events: yes
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear