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. 2009 Jul 8;2009(3):CD002759. doi: 10.1002/14651858.CD002759.pub2

Hiatt 1994.

Methods RCT with 3 groups: PRT, walking (aerobic training) and control 
 Method of randomisation: not reported 
 Assessor blinding: no 
 Participant blinding: no 
 Loss to follow‐up: 2 
 Intention‐to‐treat analysis: no 
 Post‐program follow up: no
Participants Location: USA 
 N = 29 (19 in PRT versus control) 
 Sample: people who have peripheral arterial disease and intermittent claudication 
 Age: mean 67 years 
 Inclusion criteria: intermittent claudication (disabling but stable for 3 months prior to enrolment); peripheral arterial disease 
 Exclusion criteria: leg pain at rest, ischemic ulceration, gangrene, unable to walk on the treadmill at a speed of at least 2mph; exercise capacity limited by symptoms of angina, congestive heart failure, chronic obstructive pulmonary disease, arthritis; diabetes; vascular surgery or angioplasty in the past year
Interventions PRT versus control and versus aerobic 
 1. PRT 
 Type of Ex: 5LL 
 Equipment: cuff weights 
 Intensity: high (6RM) 
 Frequency: Ex3 
 Reps/Sets: 6/3 
 Duration: 12 weeks 
 Setting: gym 
 Supervision: full 
 Adherence: not reported 
 2. Control Group: usual level of activity 
 3. Aerobic Training Group: intermittent walking on treadmill until pain subsided, 3 times per week
Outcomes Strength (Cybex dynamometer) 
 Peak Vo2 
 Comments on adverse events: no
Notes Data from PRT and aerobic training group were compared
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear