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. 2009 Jul 8;2009(3):CD002759. doi: 10.1002/14651858.CD002759.pub2

Liu‐Ambrose 2005.

Methods RCT 
 Method of randomisation: computer‐generalized list 
 Assessor blinding: yes 
 Participant blinding: not reported 
 Loss to follow‐up: 2/34 in PRT, 2/34 in stretching 
 Intention‐to‐treat analysis: yes 
 Post‐program follow up: no
Participants Location: Canada 
 N = 68 (34 in each group) 
 Sample: elder women with osteoporosis or osteopenia 
 Age: mean 79.6 years (SD = 2.1) 
 Inclusion criteria: age between 75‐85 years with low bone mass and diagnosed with osteoporosis/osteopenia 
 Exclusion criteria: living in care facilities, non‐Caucasian, exercise regularly more than 2 times a week, illness or condition that would affect balance, MMSE score lowers than 23
Interventions PRT versus control 
 1. PRT 
 Type of Ex: 4 UL, 5LL 
 Equipment: machines (Keiser Pressurized Air system) or free weights 
 Intensity: progressed from 50‐60 % of 1 RM to 75‐85% of 1 RM in 4 weeks 
 Frequency: Ex2 
 Reps/Sets: 10‐15/2 (first 3 weeks); 6‐8/2 (after week 3) 
 Duration: 25 weeks 
 Setting: community center 
 Supervision: certified fitness instructors 
 Adherence: 85% for PRT, 79% for stretching (control) 
 2. Control Group: general stretching, deep breathing and relaxation
Outcomes Primary: health related quality of life, general physical function 
 Secondary: muscle strength, gait speed, fall risk assessment 
 Comments on adverse events: yes
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear