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. 2009 Jul 8;2009(3):CD002759. doi: 10.1002/14651858.CD002759.pub2

Nelson 1994.

Methods RCT 
 Method of randomisation: not reported 
 Assessor blinding: no 
 Participant blinding: no 
 Loss to follow‐up: 1 
 Intention‐to‐treat analysis: yes 
 Post‐program follow up: no, but program had 1‐year duration
Participants Location: USA 
 N=40 
 Sample: healthy females post‐menopause 
 Age:mean 61.1 years (SD 3.7) 
 Inclusion criteria: at least 5 years post‐menopausal but not older than 70, do not engage in any regular physical training, weigh less than 130% of ideal body weight, currently non‐smoking, do not have more than one crush fracture of the spine, no history of other osteoporotic fractures, have not taken estrogen or other medications known to affect bone for 12 months, passed physical screening (including ECG during strength training session) 
 Exclusion criteria: not reported
Interventions PRT versus control 
 1.PRT 
 Type of Ex: 2 LL, 1 UL, 2Tr 
 Equipment: pneumatic resistance machines (Keiser) 
 Intensity: 80% of 1RM 
 Frequency: Ex2 
 Reps/Sets: 8/ 3 
 Program Duration: 52 weeks 
 Adherence: 87.5% 
 Setting: gym 
 Supervision: full 
 2. Control Group: asked to maintain normal level of activity, could receive the exercise program at the end of the trial
Outcomes Strength (1RM) 
 Balance (backward walking) 
 Physical activity (Harvard Alumini Questionnaire, kJ/week) 
 Comments on adverse events: yes
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear