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A. IL-27 activated both p-STAT1 and p-STAT3 in primary epithelial cells in a dose response manner 1 hr after stimulation (n=6). B. IL-13 decreased p-STAT3 activation, while having no effect on STAT1 (n=6). C. IL-27(10ng/ml) in combination with IL-13(1ng/ml) augmented p-STAT1 activation, while p-STAT3 decreased compared with IL-27 alone (n=10).
